RT Journal Article
T1 Renal Failure Associated With Intestinal Transplantation: Our Experience in Spain
A1 Calvo Pulido, Jorge
A1 Jiménez Romero, Luis Carlos
A1 Morales Ruiz, Enrique
A1 Cambra Molero, Félix
A1 Manrique Municio, Alejandro
A1 García-Sesma Pérez-Fuentes, Álvaro
A1 Loinaz Segurola, Carmelo
A1 Abradelo De Usera, Manuel
A1 Justo Alonso, Iago
A1 Caso Maestro, Óscar
A1 Alegre Torrado, C.
A1 Moreno González, Enrique
AB BackgroundRenal failure (RF) is a frequent complication in non-renal solid organ transplants. In the present study, we analyze our experience with intestinal transplants (ITx).MethodsBetween 2004 and 2012, we performed 21 ITx in 19 adult patients. Alemtuzumab was used as an induction agent followed by tacrolimus. Renal function was assessed before ITx and during the perioperative period.ResultsThe main cause for transplants was non-resectable desmoids tumors (33.3%), followed by vascular thrombosis (19%) and others. Medical complications were frequent, especially infectious diseases, which were the most common (51%). Surgical complications were also frequent, but most of them (>50%) were mild but leading to a great number of re-operations and prolonged stays in hospital. Acute rejection is very frequent (66.6%) but mild in more than 70% of the cases. Finally, RF was very frequent (68.4%; 13/19 patients) and accounted for 15.6% of all medical complications. Causes were multiple. One patient is awaiting a kidney transplant, but no other patients need renal replacement therapy at the moment. Ileostomy closure was performed in 5 of 12 patients alive, showing improved renal function in 3 of them.ConclusionsRF is a problem in ITx and is always multifactorial. Increases in hospital stay, higher morbidity and is a cause for hospital readmission. Almost all patients had an impaired renal function when discharged. Immunosuppressants and ileostomy closure as soon as possible might prevent RF.
PB Elsevier
SN 0041-1345
YR 2014
FD 2014
LK https://hdl.handle.net/20.500.14352/116021
UL https://hdl.handle.net/20.500.14352/116021
LA eng
NO Calvo Pulido, J., Jiménez Romero, C., Morales Ruíz, E., Cambra Molero, F., Manrique Municio, A., García-Sesma, A., Loinaz Segurola, C., Abradelo de Usera, M., Justo Alonso, I., Caso Maestro, O., Alegre Torrado, C., & Moreno González, E. (2014). Renal failure associated with intestinal transplantation: our experience in Spain. Transplantation proceedings, 46(6), 2140–2142. https://doi.org/10.1016/j.transproceed.2014.06.041
DS Docta Complutense
RD 30 dic 2025