TY - JOUR AU - Jones, T.D. AU - Hearn, A.R. AU - Holgate, R.G. AU - Kozub, D. AU - Fogg, M.H. AU - Carr, F.J. AU - Baker, M.P. AU - Lacadena García-Gallo, Francisco Javier AU - Gehlsen, K.R. PY - 2016 DO - 10.1093/protein/gzw045 SN - 1741-0134 (Online) ; 1741-0126 (Print) UR - https://hdl.handle.net/20.500.14352/18965 T2 - Protein Engineering, Design & Selection AB - Fungal ribotoxins that block protein synthesis can be useful warheads in the context of a targeted immunotoxin. α-Sarcin is a small (17 kDa) fungal ribonuclease produced by Aspergillus giganteus that functions by catalytically cleaving a single... LA - eng M2 - 1 PB - Oxford University Press KW - α-sarcin KW - deimmunisation KW - immunogenicity KW - immunotoxin KW - T cell epitope TI - A deimmunised form of the ribotoxin, α-sarcin,lacking CD4+ T cell epitopes and its use asan immunotoxin warhead TY - journal article ER -