RT Journal Article T1 Bloody coli: a gene cocktail in Escherichia coli O104:H4. A1 Baquero, Fernando A1 Tobes, Raquel AB A recent study published in mBio [Y. H. Grad et al., mBio 4(1):e00452-12, 2013] indicates that a rapid introgressive evolution has occurred in Escherichia coli O104:H4 by sequential acquisition of foreign genetic material involving pathogenicity traits. O104 genetic promiscuity cannot be readily explained by high population sizes. However, extensive interactions leading to cumulative assemblies of pathogenicity genes might be assured by small K-strategist populations exploiting particular intestinal niches. Next-generation sequencing technologies will be critical to detect particular "gene cocktails" as potentially pathogenic ensembles and to predict the risk of future outbreaks. SN 2150-7511 YR 2013 FD 2013-02 LK https://hdl.handle.net/20.500.14352/33315 UL https://hdl.handle.net/20.500.14352/33315 LA eng NO Comunidad de Madrid NO UniĆ³n Europea. FP7 DS Docta Complutense RD 6 abr 2025