%0 Journal Article %A Bueno Zamora, Héctor José %A Goñi, Clara %A Salguero Bodes, Rafael %A Palacios, Beatriz %A Vicent, Lourdes %A Moreno Muñoz, Guillermo %A Rosillo, Nicolás %A Varela, Luis %A Capel, Margarita %A Delgado Jiménez, Juan Francisco %A Arribas Ynsaurriaga, Fernando %A del Oro, Manuel %A Ortega, Carmen %A Bernal, Jose Luis %T Primary vs. Secondary Heart Failure Diagnosis: Differences in Clinical Outcomes, Healthcare Resource Utilization and Cost %D 2022 %U https://hdl.handle.net/20.500.14352/108761 %X Background: There is scarce information on patients with secondary heart failure diagnosis (sHF). We aimed to compare the characteristics, burden, and outcomes of sHF with those with primary HF diagnosis (pHF).Methods: Retrospective, observational study on patients ≥18 years with emergency department (ED) visits during 2018 with pHF and sHF in ED or hospital (ICD-10-CM) diagnostic codes. Baseline characteristics, 30-day and 1-year mortality, readmission and re-ED visit rates, and costs were compared between sHF and pHF.Results: Out of the 797 patients discharged home from the ED, 45.5% had sHF, and these presented lower 1-year hospitalization, re-ED visit rates, and costs. In contrast, out of the 2,286 hospitalized patients, 55% had sHF and 45% pHF. Hospitalized sHF patients had significantly (p < 0.01) greater comorbidity, lower use of recommended HF therapies, longer length of stay (10.8 ± 10.1 vs. 9.7 ± 7.9 days), and higher in-hospital and 1-year mortality (32 vs. 25.8%) with no significant differences in readmission rates and lower 1-year re-ED visit rate. Hospitalized sHF patients had higher total costs (€12,262,422 vs. €9,144,952, p < 0.001), mean cost per patient-year (€9,755 ± 13,395 vs. €8,887 ± 12,059), and average daily cost per patient.Conclusion: Hospitalized sHF patients have a worse initial prognosis, greater use of healthcare resources, and higher costs. %~