RT Journal Article
T1 Primary vs. Secondary Heart Failure Diagnosis: Differences in Clinical Outcomes, Healthcare Resource Utilization and Cost
A1 Bueno Zamora, Héctor José
A1 Goñi, Clara
A1 Salguero Bodes, Rafael
A1 Palacios, Beatriz
A1 Vicent, Lourdes
A1 Moreno Muñoz, Guillermo
A1 Rosillo, Nicolás
A1 Varela, Luis
A1 Capel, Margarita
A1 Delgado Jiménez, Juan Francisco
A1 Arribas Ynsaurriaga, Fernando
A1 del Oro, Manuel
A1 Ortega, Carmen
A1 Bernal, Jose Luis
AB Background: There is scarce information on patients with secondary heart failure diagnosis (sHF). We aimed to compare the characteristics, burden, and outcomes of sHF with those with primary HF diagnosis (pHF).Methods: Retrospective, observational study on patients ≥18 years with emergency department (ED) visits during 2018 with pHF and sHF in ED or hospital (ICD-10-CM) diagnostic codes. Baseline characteristics, 30-day and 1-year mortality, readmission and re-ED visit rates, and costs were compared between sHF and pHF.Results: Out of the 797 patients discharged home from the ED, 45.5% had sHF, and these presented lower 1-year hospitalization, re-ED visit rates, and costs. In contrast, out of the 2,286 hospitalized patients, 55% had sHF and 45% pHF. Hospitalized sHF patients had significantly (p < 0.01) greater comorbidity, lower use of recommended HF therapies, longer length of stay (10.8 ± 10.1 vs. 9.7 ± 7.9 days), and higher in-hospital and 1-year mortality (32 vs. 25.8%) with no significant differences in readmission rates and lower 1-year re-ED visit rate. Hospitalized sHF patients had higher total costs (€12,262,422 vs. €9,144,952, p < 0.001), mean cost per patient-year (€9,755 ± 13,395 vs. €8,887 ± 12,059), and average daily cost per patient.Conclusion: Hospitalized sHF patients have a worse initial prognosis, greater use of healthcare resources, and higher costs.
PB Frontiers
YR 2022
FD 2022-03-17
LK https://hdl.handle.net/20.500.14352/108761
UL https://hdl.handle.net/20.500.14352/108761
LA eng
NO Bueno H, Goñi C, Salguero-Bodes R, Palacios B, Vicent L, Moreno G, Rosillo N, Varela L, Capel M, Delgado J, Arribas F, del Oro M, Ortega C and Bernal JL (2022) Primary vs. Secondary Heart Failure Diagnosis: Differences in Clinical Outcomes, Healthcare Resource Utilization and Cost. Front. Cardiovasc. Med. 9:818525. doi: 10.3389/fcvm.2022.818525
NO CM20/00104FPU18/03606
NO AstraZeneca Spain
NO Instituto de Salud Carlos III
NO España. Ministerio de Educación
DS Docta Complutense
RD 8 jun 2025