%0 Journal Article %A Gutiérrez Estévez, Manuel %A Cicuéndez Maroto, Mónica %A Crespo, Julián %A Serrano-López, Juana %A Colilla Nieto, Montserrat %A Fernández-Acevedo, Claudio %A Oroz-Mateo, Tamara %A Rada-Leza, Amaia %A González Ortiz, Blanca %A Izquierdo Barba, Isabel %A Vallet Regí, María Dulce Nombre %T Large-scale production of superparamagnetic iron oxide nanoparticles by flame spray pyrolysis: in vitro biological evaluation for biomedical applications %D 2023 %@ 0021-9797 %U https://hdl.handle.net/20.500.14352/87969 %X Despite the large number of synthesis methodologies described for superparamagnetic iron oxide nanoparticles(SPIONs), the search for their large-scale production for their widespread use in biomedical applications remainsa mayor challenge. Flame Spray Pyrolysis (FSP) could be the solution to solve this limitation, since it allows thefabrication of metal oxide nanoparticles with high production yield and low manufacture costs. However, to ourknowledge, to date such fabrication method has not been upgraded for biomedical purposes. Herein, SPIONs %~