RT Journal Article T1 Large-scale production of superparamagnetic iron oxide nanoparticles by flame spray pyrolysis: in vitro biological evaluation for biomedical applications A1 Gutiérrez Estévez, Manuel A1 Cicuéndez Maroto, Mónica A1 Crespo, Julián A1 Serrano-López, Juana A1 Colilla Nieto, Montserrat A1 Fernández-Acevedo, Claudio A1 Oroz-Mateo, Tamara A1 Rada-Leza, Amaia A1 González Ortiz, Blanca A1 Izquierdo Barba, Isabel A1 Vallet Regí, María Dulce Nombre AB Despite the large number of synthesis methodologies described for superparamagnetic iron oxide nanoparticles(SPIONs), the search for their large-scale production for their widespread use in biomedical applications remainsa mayor challenge. Flame Spray Pyrolysis (FSP) could be the solution to solve this limitation, since it allows thefabrication of metal oxide nanoparticles with high production yield and low manufacture costs. However, to ourknowledge, to date such fabrication method has not been upgraded for biomedical purposes. Herein, SPIONs PB Elsevier SN 0021-9797 YR 2023 FD 2023-07-04 LK https://hdl.handle.net/20.500.14352/87969 UL https://hdl.handle.net/20.500.14352/87969 LA eng NO Acuerdo transformativo NO European Union NO Ministerio de Ciencia e Innovacion de España DS Docta Complutense RD 10 abr 2025