TY  - JOUR
AU  - González Martín-Moro, Julio
AU  - Gómez Sanz, Fernando J.
AU  - Bravo Nuevo, Arturo
AU  - García Cabezas, Miguel Ángel
PY  - 2025
DO  - 10.1016/j.mehy.2025.111623
UR  - https://hdl.handle.net/20.500.14352/120270
T2  - Medical Hypotheses
AB  - Leber hereditary optic neuropathy (LHON) is a mitochondrial disorder that leads to rapid, often irreversible central visual loss. While the mitochondrial inheritance of LHON was clarified in 1988, key aspects of its pathophysiology remain unexplained,...
LA  - eng
PB  - Elsevier
KW  - Optic nerve
KW  - Hereditary optic neuropathy
KW  - Photic maculopathy
KW  - Retina ganglion cell layer
KW  - Light toxicity
KW  - Mitochondrial DNA
TI  - A theory on the pathogenesis of Leber hereditary optic neuropathy: Two hits and the role of light toxicity
TY  - journal article
VL  - 198
ER  -