TY - JOUR AU - Brioche, T. AU - Kireev, Roman AU - Cuesta Sancho, Sara AU - Gratas Delamarche, A. AU - Fernández-Tresguerres Hernández, Jesús Ángel AU - Gómez Cabrera, M. C. AU - Viña Ribes, Jose PY - 2013 DO - 10.1093/gerona/glt187 SN - 1079-5006 UR - https://hdl.handle.net/20.500.14352/99737 T2 - The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences AB - The aim of our study was to elucidate the role of growth hormone (GH) replacement therapy in three of the main mechanisms involved in sarcopenia: alterations in mitochondrial biogenesis, increase in oxidative stress, and alterations in protein... LA - eng M2 - 1186 PB - Oxford University Press KW - IGF-1 KW - Mitochondrial biogenesis KW - Myostatin KW - p70S6K TI - Growth hormone replacement therapy prevents sarcopenia by a dual mechanism: improvement of protein balance and of antioxidant defenses TY - journal article VL - 69 ER -