RT Journal Article T1 Cause and Long-Term Outcome of Cardiac Tamponade A1 Sánchez Enrique, Cristina A1 Nuñez Gil, Iván J. A1 Viana Tejedor, Ana Teresa A1 De Agustín Loeches, José Alberto A1 Vivas Balcones, Luis David A1 Palacios Rubio, Julián A1 Vilchez, Jean Paul A1 Cecconi, Alberto A1 Macaya Miguel, Carlos A1 Fernández Ortiz, Antonio Ignacio AB Cardiac tamponade is a life-threatening condition, whose current specific cause and outcome are unknown. Our purpose was to analyze it. We performed a retrospective observational study with prospective follow-up data including 136 consecutive patients admitted with diagnosis of cardiac tamponade, from 2003 to 2013. We thoroughly recorded variables as clinical features, drainage/pericardiocentesis, fluid characteristics, and long-term events (new cardiac tamponade ± death). The median age was 65 ± 17 years (55% men). In the baseline characteristics, 70% were no smokers, 12% were on anticoagulation, and 13 had suffered a previous myocardial infarction. In the preceding month, 15 patients had undergone a cardiac catheterization, 5 cardiac surgery, and 5 pacemaker insertion. Fever was observed in 16% of patients and 21% displayed other inflammatory symptoms. In 81% of patients, pericardiocentesis was needed. The fluid was hemorrhagic or a transudate in the majority, with positive cytology in 15% and bacteria in 3.7%. Main causes were malignancy (32%), infection (24%), idiopathic (16%), iatrogenic (15%), postmyocardial infarction (7%), uremic (4%), and other causes (2%). After a maximum follow-up of 10.4 years, cardiac tamponade recurred in 10% of the cases (62% in the neoplastic group) and the 48% of patients died (89% in the neoplastic cohort). In conclusion, most cardiac tamponades are due to malignancy, having this specific cause a poorer outcome, probably as a manifestation of an advanced disease. The rest of causes, after an aggressive intensive management, have a good prognosis, especially the iatrogenic. PB Elsevier SN 0002-9149 YR 2015 FD 2015-12-07 LK https://hdl.handle.net/20.500.14352/133634 UL https://hdl.handle.net/20.500.14352/133634 LA eng NO Sánchez-Enrique, C., Nuñez-Gil, I. J., Viana-Tejedor, A., De Agustín, A., Vivas, D., Palacios-Rubio, J., Vilchez, J. P., Cecconi, A., Macaya, C., & Fernández-Ortiz, A. (2016). Cause and Long-Term Outcome of Cardiac Tamponade. The American journal of cardiology, 117(4), 664–669. https://doi.org/10.1016/j.amjcard.2015.11.023 DS Docta Complutense RD 18 mar 2026