TY - JOUR AU - Moreno Ruperez, Álvaro AU - Priego Cuadra, Teresa AU - González-Nicolás González, María Ángeles, María Angeles AU - López-Calderón Barreda, Asunción AU - Lázaro, Alberto AU - Martín Velasco, Ana Isabel PY - 2022 DO - 10.3390/ijms23073641 SN - 1422-0067 UR - https://hdl.handle.net/20.500.14352/72281 T2 - International Journal of Molecular Sciences AB - Sepsis increases glucocorticoid and decreases IGF-1, leading to skeletal muscle wasting and cachexia. Muscle atrophy mainly takes place in locomotor muscles rather than in respiratory ones. Our study aimed to elucidate the mechanism responsible for... LA - eng M2 - 3641 PB - MDPI KW - Sepsis KW - Inflammation KW - Muscle wasting KW - Glucocorticoids signaling KW - HDAC4-myogenin KW - IGF-1 KW - IGFBP3 KW - Atrogens KW - Autophagy TI - Role of Glucocorticoid Signaling and HDAC4 Activation in Diaphragm and Gastrocnemius Proteolytic Activity in Septic Rats. TY - journal article VL - 23 ER -