RT Journal Article
T1 Optimal management of diabetic foot osteomyelitis: challenges and solutions
A1 Lázaro Martínez, José Luis
A1 García Álvarez, Yolanda
A1 Tardaguila García, Aroa
A1 García Morales, Esther Alicia
AB Purpose: Diabetic foot osteomyelitis (DFO) is the most frequent infection associated with diabetic foot ulcers, occurs in >20% of moderate infections and 50%–60% of severe infections, and is associated with high rates of amputation. DFO represents a challenge in both diagnosis and therapy, and many consequences of its condition are related to late diagnosis, delayed referral, or ill-indicated treatment. This review aimed to analyze the current evidence on DFO management and to discuss advantages and disadvantages of different treatment options.Methods: A narrative review of the evidence was begun by searching Medline and PubMed databases for studies using the keywords “management”, “diabetic foot”, “osteomyelitis”, and “diabetic foot osteomyelitis” from 2008 to 2018.Results: We found a great variety of studies focusing on both medical and surgical therapies showing a similar rate of effectiveness and outcomes; however, the main factors in choosing one over the other seem to be associated with the presence of soft-tissue infection or ischemia and the clinical presentation of DFO.Conclusion: Further randomized controlled trials with large samples and long-term follow-up are necessary to demonstrate secondary outcomes, such as recurrence, recurrent ulceration, and reinfection associated with both medical and surgical options.
PB Dovepress
YR 2019
FD 2019-06-21
LK https://hdl.handle.net/20.500.14352/124281
UL https://hdl.handle.net/20.500.14352/124281
LA eng
NO Lázaro Martínez JL, García Álvarez Y, Tardáguila-García A, García Morales E. Optimal management of diabetic foot osteomyelitis: challenges and solutions. Diabetes Metab Syndr Obes. 2019;12:947-959 https://doi.org/10.2147/DMSO.S181198
DS Docta Complutense
RD 31 dic 2025