RT Book, Section T1 Control of Legionella pneumophila by disinfectants. Effects of sodium hypochlorite against persistent strains A1 García Esteban, María Teresa A1 Martín González, Ana María A1 Pelaz, Carmen AB Legionella pneumophila is the causative agent of Legionnaires' disease. Legionella is ubiquitous in natural freshwater ecosystems and it is frequently found in artificial aquatic systems. Due to its wide distribution and the impact on the human health, there have been applied many different physical and/or chemical treatments to control Legionella, especially in man-made water systems. We have reviewed the efficiency, advantages and limitations on chlorine and other disinfectants to control this important human pathogen. Besides, we have evaluated experimentally the effects of both, shock and continous treatments of chlorine (sodium hypochlorite) on viability and persistence of four different isolates of L. pneumophila sg1. We have demonstrated that both treatments were effective against Legionella pneumophila only when the bacteria were not previouly exposed to chlorine. We have also showed how under unfavourable environmental conditions such as disinfection treatments, some cells of populations might have differentiated to the viable non culturable stage. These findings should be considered in order to design effective methodologies to detect and prevent the presence of L. pneumophila in diverse natural and artificial aquatic habitats. PB World Scientific Publishing Co. Pte. Ltd. SN 9789812837547 SN 9789812837554 YR 2009 FD 2009-01 LK https://hdl.handle.net/20.500.14352/130480 UL https://hdl.handle.net/20.500.14352/130480 LA eng NO Garcia, M. T., Martín-González, A., & Pelaz, C. (2009). Control of Legionella pneumophila by disinfectants. Effects of sodium hypochlorite against persistent strains. Current Research Topics in Applied Microbiology and Microbial Biotechnology, 198-199. https://doi.org/10.1142/9789812837554_0041 NO Proceedings of the II International Conference on Environmental, Industrial and Applied Microbiology (BioMicroWorld2007), University of Seville, Spain, 28 November – 1 December 2007 DS Docta Complutense RD 20 ene 2026