RT Journal Article
T1 A model for acid-mediated tumour growth with nonlinear acid production term
A1 Holder, Andrew B.
A1 Rodrigo, Marianito R.
A1 Herrero, Miguel A.
AB This article considers a mathematical model for tumour growth based on an acid-mediated hypothesis, i.e. the assumption that tumour progression is facilitated by acidification of the region around the tumour-host interface. The resulting destruction of the normal tissue environment promotes tumour growth. We will derive and analyse a reaction–diffusion model for tumour progression that includes different aspects of pathological and healthy cell metabolism to check tumour growth. Our results can provide insights into the governing dynamics of invasive processes that may suggest possible intervention strategies, leading to the design of new and better experiments or treatments.
PB Elsevier
SN 0096-3003
YR 2014
FD 2014-01-15
LK https://hdl.handle.net/20.500.14352/33489
UL https://hdl.handle.net/20.500.14352/33489
LA eng
NO MINECO (Spain)
NO University of Wollongong
DS Docta Complutense
RD 23 abr 2025