RT Journal Article
T1 Approaches to evaluate the specific immune responses to SARS-CoV-2
A1 López Gómez, Ana
A1 Peláez Prestel, Héctor Fernando
A1 Juárez Martín-Delgado, Ignacio
AB The SARS-CoV-2 pandemic has a huge impact on public health and global economy, meaning an enormous scientific, political, and social challenge. Studying how infection or vaccination triggers both cellular and humoral responses is essential to know the grade and length of protection generated in the population. Nowadays, scientists and authorities around the world are increasingly concerned about the arrival of new variants, which have a greater spread, due to the high mutation rate of this virus. The aim of this review is to summarize the different techniques available for the study of the immune responses after exposure or vaccination against SARS-CoV-2, showing their advantages and limitations, and proposing suitable combinations of different techniques to achieve extensive information in these studies. We wish that the information provided here will helps other scientists in their studies of the immune response against SARS-CoV-2 after vaccination with new vaccine candidates or infection with upcoming variants.
PB Elsevier
SN 0264-410X
YR 2023
FD 2023-10
LK https://hdl.handle.net/20.500.14352/92459
UL https://hdl.handle.net/20.500.14352/92459
LA eng
NO Lopez-Gomez A, Pelaez-Prestel HF, Juarez I. Approaches to evaluate the specific immune responses to SARS-CoV-2. Vaccine. 2023 Oct 13;41(43):6434-6443. doi: 10.1016/j.vaccine.2023.09.033
DS Docta Complutense
RD 8 abr 2025