RT Journal Article T1 Deoxynivalenol degradation in wheat kernels by exposition to ammonia vapours: a tentative strategy for detoxification A1 Borràs-Vallverdú, Bernat A1 Ramos Ruiz, Amparo A1 Marín, Sonia A1 Sanchis, Vicente A1 Rodríguez Bencomo, Juan José AB Deoxynivalenol (DON) is a mycotoxin produced mainly by Fusarium species and occurs predominantly in cereal grains such as wheat. Due to its toxic effects, in the European Union DON content in unprocessed cereals and processed cereal-based products for human consumption has been regulated, and recommended maximum limits have been established for animal feed. In this study, a method for degrading DON on wheat kernels, by exposition to ammonia (NH3) vapours, was optimized. Results have shown that with a simple treatment with ammonia vapours at 90 °C (for 2 h), degradations higher than 75% were achieved in kernels affected by a moderated contamination up to 2000 μg/kg DON. The study of the reaction between DON and NH3 allowed us to tentatively establish the structure of possible degradation products. In addition, in silico evaluation indicated, in general, lower toxicity and biological effects for the degradation products than for DON. PB Elsevier SN 0956-7135 YR 2020 FD 2020 LK https://hdl.handle.net/20.500.14352/93076 UL https://hdl.handle.net/20.500.14352/93076 LA eng NO Borràs-Vallverdú, Bernat, et al. «Deoxynivalenol Degradation in Wheat Kernels by Exposition to Ammonia Vapours: A Tentative Strategy for Detoxification». Food Control, vol. 118, diciembre de 2020, p. 107444. https://doi.org/10.1016/j.foodcont.2020.107444. NO Ministerio de Ciencia, Innovación y Universidades (España) DS Docta Complutense RD 1 sept 2024