RT Journal Article T1 Foot Revascularization Avoids Major Amputation in Persons with Diabetes and Ischaemic Foot Ulcers A1 Meloni, Marco A1 Morosetti, Daniele A1 Giurato, Laura A1 Stefanini, Matteo A1 Loreni, Giorgio A1 Doddi, Marco A1 Panunzi, Andrea A1 Bellia, Alfonso A1 Gandini, Roberto A1 Brocco, Enrico A1 Lázaro Martínez, José Luis A1 Lauro, Davide A1 Uccioli, Luigi AB The study aims to evaluate the effectiveness of foot revascularization in persons with diabetic foot ulcers (DFUs) and below-the-ankle (BTA) arterial disease. Consecutive patients referred for a new active ischaemic DFU requiring lower limb revascularization were considered. Among those, only patients with a BTA arterial disease were included. Revascularization procedures were retrospectively analysed: in the case of successful foot revascularization (recanalization of pedal artery, or plantar arteries or both) or not, patients were respectively divided in two groups, successful foot perfusion (SFP) and failed foot perfusion (FFP). Healing, minor and major amputation at 12 months of follow-up were evaluated and compared. Eighty patients (80) were included. The mean age was 70.5 ± 10.9 years, 55 (68.7%) were male, 72 (90%) were affected by type 2 diabetes with a mean duration of 22.7 ± 11.3 years. Overall 45 (56.2%) patients healed, 47 (58.7%) had minor amputation and 13 (16.2%) major amputation. Outcomes for SFP and FFP were respectively: healing (89.3 vs. 9.1%, p < 0.0001), minor amputation (44.7 vs. 78.8%, p = 0.0001), major amputation (2.1 vs. 36.3%, p < 0.0001). Failed foot revascularization resulted an independent predictor of non-healing, minor amputation, and major amputation. Foot revascularization is mandatory to achieve healing and avoid major amputation in persons with ischaemic DFU and BTA arterial disease. PB MDPI SN 2077-0383 YR 2021 FD 2021 LK https://hdl.handle.net/20.500.14352/87231 UL https://hdl.handle.net/20.500.14352/87231 LA eng DS Docta Complutense RD 10 abr 2025