RT Journal Article T1 Treatment of Plantar Warts with a Nitric-Zinc Complex Solution: A Review of 72 Cases A1 García Oreja, Sara A1 Álvaro Afonso, Francisco Javier A1 Vigara Aranda, Paula A1 Paramio Rodriguez, Guillermo A1 Leon Herce, Diego A1 Lázaro Martínez, José Luis AB Background: There are multiple conservative treatment options for plantar warts, but none have proven to be universally effective. Nitric acid is often used empirically by podiatrists in the treatment of plantar warts. A novel medical device or topical solution of nitric–zinc complex solution (NZCS) could potentially offer an effective and safe alternative for the targeted treatment of plantar warts. Objective: To observe the rate of complete healing of NZCS in a series of plantar wart cases and to establish the minimum number of product applications and time needed for healing. This will help standardize and protocolize its use. Methods: A descriptive study was conducted involving 72 patients who exhibited symptoms of plantar warts. These patients underwent chemical treatment using a nitric–zinc complex. Results: The cure rate with NZCS was 59.2%. The average number of NZCS applications was 5.9 ± 3.0 and the mean duration of treatment was 9.4 ± 7.1 weeks. A recurrence rate of 6.7% was observed. Conclusions: The topical solution of the nitric–zinc complex is an effective treatment for plantar warts, which can be considered a first-line treatment option in the general population. PB MDPI SN 1999-4915 YR 2024 FD 2024-08-16 LK https://hdl.handle.net/20.500.14352/118921 UL https://hdl.handle.net/20.500.14352/118921 LA eng NO Garcia-Oreja, S.; Alvaro-Afonso, F.J.; Vigara-Aranda, P.; Paramio-Rodriguez, G.; Leon-Herce, D.; Lazaro-Martinez, J.L. Treatment of Plantar Warts with a Nitric-Zinc Complex Solution: A Review of 72 Cases. Viruses 2024, 16, 1307. https://doi.org/10.3390/v16081307 NO Universidad Complutense de Madrid NO Banco Santander DS Docta Complutense RD 4 abr 2025