TY - JOUR AU - Muñoz, Juan José AU - Tobajas, Esther AU - Juara, Sonia AU - Montero Herradón, Sara AU - Zapata González, Agustín Gregorio PY - 2019 DO - 10.1007/s00418-019-01818-z SN - 1432-119X UR - https://hdl.handle.net/20.500.14352/12355 T2 - Histochemistry and Cell Biology AB - The mechanisms that determine the commitment of thymic epithelial precursors to the two major thymic epithelial cell lineages, cTECs and mTECs, remain unknown. Here we show that FoxN1 nu mutation, which abolishes thymic epithelium differentiation,... AB - Dos factores regulan el desarrollo del epitelio tímico, el factor de transcripción Foxn1 y las interacciones célula-célula entre timocitos y epitelio tímico, imprescindible a su vez para la maduración funcional de los timocitos. El trabajo re-evalúa... LA - eng M2 - 397 PB - Springer KW - Thymus KW - branching morphogenesis KW - tubulogenesis KW - thymic epithelium KW - FoxN1 TI - FoxN1 mediates thymic cortex–medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis TY - journal article VL - 152 ER -