RT Journal Article
T1 The Stressed CNS: When Glucocorticoids Aggravate Inflammation
A1 Sorrells, Shawn
A1 Caso Fernández, Javier Rubén
A1 Munhoz, Carolina
A1 Sapolsky, Robert
AB Glucocorticoids (GCs) are hormones released during the stress response that are well known for their immunosuppressive and anti-inflammatory properties; however, recent advances have uncovered situations wherein they have effects in the opposite direction. The CNS is a particularly interesting example, both because of its unique immune environment, and because GCs affect immune responses differently in different brain regions. In this minireview we discuss the contexts wherein GCs increase CNS inflammation and point out directions for future investigation.
PB Elsevier
SN 0896-6273
YR 2009
FD 2009-10-15
LK https://hdl.handle.net/20.500.14352/134344
UL https://hdl.handle.net/20.500.14352/134344
LA eng
NO Sorrells, S. F., Caso, J. R., Munhoz, C. D., & Sapolsky, R. M. (2009). The stressed CNS: when glucocorticoids aggravate inflammation. Neuron, 64(1), 33–39. https://doi.org/10.1016/j.neuron.2009.09.032
NO Adler Foundation
DS Docta Complutense
RD 6 abr 2026