RT Journal Article T1 Temperature-related excess mortality in German cities at 2 °C and higher degrees of global warming A1 Huber, Veronika A1 krummenauer, Linda A1 Peña-Oritz, Cristina A1 Lange, Stefan A1 Gasparrini, Antonio A1 Vicedo-Cabrera, Ana M. A1 García Herrera, Ricardo Francisco A1 Frieler, Katja AB Background: Investigating future changes in temperature-related mortality as a function of global mean temperature (GMT) rise allows for the evaluation of policy-relevant climate change targets. So far, only few studies have taken this approach, and, in particular, no such assessments exist for Germany, the most populated country of Europe.Methods: We assess temperature-related mortality in 12 major German cities based on daily time-series of allcause mortality and daily mean temperatures in the period 1993–2015, using distributed-lag non-linear models in a two-stage design. Resulting risk functions are applied to estimate excess mortality in terms of GMT rise relative to pre-industrial levels, assuming no change in demographics or population vulnerability.Results: In the observational period, cold contributes stronger to temperature-related mortality than heat, with overall attributable fractions of 5.49% (95%CI: 3.82–7.19) and 0.81% (95%CI: 0.72–0.89), respectively. Future projections indicate that this pattern could be reversed under progressing global warming, with heat-related mortality starting to exceed cold-related mortality at 3 °C or higher GMT rise. Across cities, projected net increases in total temperature-related mortality were 0.45% (95%CI: −0.02–1.06) at 3 °C, 1.53% (95%CI: 0.96–2.06) at 4 °C, and 2.88% (95%CI: 1.60–4.10) at 5 °C, compared to today's warming level of 1 °C. By contrast, no significant difference was found between projected total temperature-related mortality at 2 °C versus 1 °C of GMT rise.Conclusions: Our results can inform current adaptation policies aimed at buffering the health risks from increased heat exposure under climate change. They also allow for the evaluation of global mitigation efforts in terms of local health benefits in some of Germany's most populated cities. PB Academic Press Inc. Elsevier Science SN 0013-9351, ESSN: 1096-0953 YR 2020 FD 2020-07 LK https://hdl.handle.net/20.500.14352/6479 UL https://hdl.handle.net/20.500.14352/6479 LA eng NO © 2020 The Authors. We would like to thank Urban Janisch from the Research Data Centres of the Federation and the Federal States of Germany for his advice in assembling the death count statistics. DS Docta Complutense RD 9 abr 2025