TY  - JOUR
AU  - Alencar, Nelson
AU  - Sola, Irene
AU  - Linares Gómez, María
AU  - Juárez-Jiménez, Jordi
AU  - Pont, Caterina
AU  - Viayna, Antonio
AU  - Vílchez, David
AU  - Sampedro, Cristina
AU  - Abad, Paloma
AU  - Pérez-Benavente, Susana
AU  - Lameira, Jerónimo
AU  - Bautista Santa Cruz, José Manuel
AU  - Muñoz-Torrero, Diego
AU  - Luque, F. Javier
PY  - 2018
DO  - 10.1016/j.ejmech.2018.01.044
SN  - 0223-5234
UR  - https://hdl.handle.net/20.500.14352/93568
T2  - European Journal of Medicinal Chemistry
AB  - In Plasmodium falciparum the bifunctional enzyme glucose-6-phosphate dehydrogenase‒6-phosphogluconolactonase (PfG6PD‒6PGL) is involved in the catalysis of the first reaction of the pentose phosphate pathway. Since this enzyme has a key role in...
LA  - eng
M2  - 108
PB  - Elsevier
KW  - Malaria
KW  - Glucose-6-phosphate dehydrogenase
KW  - Plasmodium falciparum
KW  - Homology modeling
KW  - Selective inhibitors
KW  - Drug design
TI  - First homology model of Plasmodium falciparum glucose-6-phosphate dehydrogenase: Discovery of selective substrate analog-based inhibitors as novel antimalarial agents
TY  - journal article
VL  - 146
ER  -