RT Journal Article T1 Quality of Life and Anxiety in Age Macular Degeneration Patients: A Cross-Sectional Study A1 Caballe Fontanet, Daniel A1 Álvarez Peregrina, Cristina A1 Busquet Duran, Neus A1 Pedemonte Sarrias, Eduard A1 Andreu Vázquez, Cristina A1 Sánchez Tena, Miguel Ángel AB (1) Background: Chronic diseases affect patients’ quality of life. Age Macular Degeneration (AMD) is one of the most prevalent chronic ocular diseases. The study aims to measure the anxiety and quality of life related to vision in patients with AMD, as well as the relationship with other visual and demographic parameters. (2) Methods: Prospective cross-sectional study in AMD patients. Visual acuity (VA), contrast sensitivity (CS), line difference in the Colenbrander test, and the degree of pathology were measured. Other variables such as gender, age, and time from the diagnosis were also collected. Anxiety was measured with the Spielberger State-Trait Anxiety Inventory (STAI) and quality of life with the National Eye Institute Visual Function Questionnaire (NEI VFQ-25). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist was followed. (3) Results: Patients with higher punctuation in Trait STAI showed lower punctuation in NEI VFQ-25 questionnaire (Spearman coefficient −0.415; p = 0.001). The variables VA, CS, and age were correlated to the quality of life. The relationship between trait anxiety and subscales of NEI VFQ-25 was significant for all subscales (p < 0.05), except for social functioning, peripheral vision, general vision, ocular pain, and driving. (4) Conclusions: AMD patients with higher levels of anxiety show a decrease in their quality of life. The quality of life of AMD patients depends on their VA and CS. PB MPDI SN 1660-4601 YR 2022 FD 2022-01-12 LK https://hdl.handle.net/20.500.14352/72073 UL https://hdl.handle.net/20.500.14352/72073 LA eng DS Docta Complutense RD 5 abr 2025