TY  - JOUR
AU  - Marín Ramos, Nagore Isasbel
AU  - Piñar Pinedo, María del Carmen
AU  - Vázquez Villa, María Del Henar
AU  - Martín-Fontecha Corrales, María Del Mar
AU  - Gonzalez Wong, Ángel
AU  - Canales Mayordomo, María Ángeles
AU  - Algar Lizana, Sergio
AU  - Mayo Mariscal de Gante, Paloma P.
AU  - Jiménez-Barbero, Jesús
AU  - Gajate Fraile, Consuelo
AU  - Mollinedo García, Faustino
AU  - Pardo Carrasco, Leonardo
AU  - Ortega Gutiérrez, Silvia
AU  - Viso Beronda, Alma
AU  - López Rodríguez, María Luz
PY  - 2017
DO  - 10.1002/chem.201604905
SN  - 0947-6539
UR  - https://hdl.handle.net/20.500.14352/18289
T2  - Chemistry: a european journal
AB  - Despite more than three decades of intense effort, no anti-Ras therapies have reached clinical application. Contributing to this failure has been an underestimation of Ras complexity and a dearth of structural information. In this regard, recent...
LA  - eng
M2  - 1676
PB  - Wiley
KW  - Cancer
KW  - Drug design
KW  - Inhibitors
KW  - Medicinal chemistry
KW  - Proteins
TI  - Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling
TY  - journal article
VL  - 23
ER  -