RT Journal Article
T1 Solvothermal synthesis and characterization of ytterbium/iron mixed oxide nanoparticles with potential functionalities for applications as multiplatform contrast agent in medical image techniques
A1 Yeste, Pilar
A1 Fernández Ponce, Cecilia
A1 Félix, Eduardo
A1 Tinoco Rivas, Miguel
A1 Fernández Cisnal, Ricardo
A1 García Villar, Cristina
A1 Pfaff, Cathrin
A1 Kriwet, Jürgen
A1 Natividad, Eva
A1 Cauqui, Miguel Ángel
A1 García Cózar, Francisco José
A1 Litrán, Rocío
A1 Bomati Miguel, Óscar
AB A solvothermal route to prepare Glutathione capped hybrid ytterbium/iron oxide nanoparticles with potential applications as multiplatform contrast agent in medical image techniques has been developed. The influence of ytterbium/iron molar ratio used as precursor, as well as the degree of the autoclave filling on the structural and morphological characteristics of the obtained nanoparticles has been extensively studied. Although all nanoparticles present similar composition, with YbFeO3 being the majority phase, size and morphology of the as synthetized nanoparticles are highly influenced by the critical temperature and by the over -saturation reached during the solvothermal process. We have demonstrated that glutathione properly functionalizes the hybrid nanoparticles, increasing their colloidal stability and decreasing their cytotoxicity. Additionally, they show good imaging in magnetic resonance and X-ray computerized tomography, thereby indicating promising potential as a dual contrast agent. This work presents, for the first time, glutathione functionalized ytterbium/iron oxide nanoparticles with potential applications in Biomedicine.
SN 0272-8842
YR 2022
FD 2022
LK https://hdl.handle.net/20.500.14352/94755
UL https://hdl.handle.net/20.500.14352/94755
LA eng
NO Yeste, M. P., et al. «Solvothermal Synthesis and Characterization of Ytterbium/Iron Mixed Oxide Nanoparticles with Potential Functionalities for Applications as Multiplatform Contrast Agent in Medical Image Techniques». Ceramics International, vol. 48, n.o 21, noviembre de 2022, pp. 31191-202. https://doi.org/10.1016/j.ceramint.2022.06.194.
DS Docta Complutense
RD 8 abr 2025