RT Journal Article
T1 Management and outcome of liver abscesses after liver transplantation
A1 Justo Alonso, Iago
A1 Jiménez Romero, Luis Carlos
A1 Manrique Municio, Alejandro
A1 Caso Maestro, Óscar
A1 Calvo Pulido, Jorge
A1 Cambra Molero, Félix
A1 Marcacuzco Quinto, Alberto Alejandro
AB Background: Liver abscess after orthotopic liver transplantation (OLT) is a rare, life-threatening complication. The aim of this study is to analyze the incidence, risk factors, clinical manifestations, treatment and outcomes of liver abscesses after OLT.Methods: We perform a retrospective review of the patients who developed one or more liver abscesses among a series of 984 patients who underwent OLT between January 2000 and December 2016.Results: Fourteen patients (1.5%) developed 18 episodes of liver abscesses, and the median time from OLT to the diagnosis of liver abscess was 39.7 months. Major predisposing factors were biliary strictures in 11 patients, hepatic artery thrombosis in 8, re-OLT in 3, choledochojejunostomy in 2, living donor OLT in 2, donor after cardiac death in 1, split liver in 1, and liver biopsy in 1. All patients were managed by intravenous antibiotics; percutaneous drainage was performed in 10 patients, while 2 patients underwent re-OLT. The mortality rate related to liver abscesses was 21.4%. The mean hospital stay was 30 ± 19 days, and during a mean follow-up of 93 ± 78 months, three other patients died.Conclusions: Liver abscesses must be managed with antibiotic therapy and percutaneous drainage, but when these conservative measures fail (persistent abscess and sepsis), a re-OLT must be performed in order to prevent the high mortality associated with this severe complication.
PB Wiley
SN 0364-2313
YR 2018
FD 2018-04-09
LK https://hdl.handle.net/20.500.14352/98801
UL https://hdl.handle.net/20.500.14352/98801
LA eng
NO Justo I, Jiménez-Romero C, Manrique A, Caso O, Calvo J, Cambra F, Marcacuzco A. Management and Outcome of Liver Abscesses After Liver Transplantation. World J Surg. 2018 Oct;42(10):3341-3349. doi: 10.1007/s00268-018-4622-x
DS Docta Complutense
RD 10 abr 2025