RT Book, Section
T1 The endocannabinoid system: Anorexia nervosa and binge eating disorder
A1 Scherma, María
A1 Satta, Valentina
A1 Fratta, Walter
A1 Fadda, Paola
A2 Fattore, Liana
AB Eating disorders (EDs) include a range of chronic and disabling related psychiatric pathologies characterized by aberrant eating patterns or weight-control behavior and distorted body image. The etiology of EDs is complex and not yet completely understood. The endocannabinoid system has been widely reported to be involved in the regulation of feeding and energy balance, and cannabinoid type-1 receptors (CB1Rs) are expressed in many brain regions that control food intake. Animal and human studies indicate that CB1R agonists possess orexigenic effects enhancing appetite and increasing the perceived reward value of food. Conversely, CB1R antagonists have been shown to inhibit food intake. Previous clinical and preclinical evidence has led us to hypothesize a link between defects in the endocannabinoid system and EDs and supports the development of drugs that modulate this system in ED-related pathologies.
PB Elsevier
SN 9780124170414
YR 2015
FD 2015
LK https://hdl.handle.net/20.500.14352/132294
UL https://hdl.handle.net/20.500.14352/132294
LA eng
NO Maria Scherma, Valentina Satta, Walter Fratta, Paola Fadda, Chapter 16 - The endocannabinoid system: Anorexia nervosa and binge eating disorder, Editor(s): Liana Fattore, Cannabinoids in Neurologic and Mental Disease, Academic Press, 2015, Pages 389-413, ISBN 9780124170414, https://doi.org/10.1016/B978-0-12-417041-4.00016-3.
DS Docta Complutense
RD 19 mar 2026