TY - JOUR AU - Fernández Albarral, José AU - Simón-García, Ana AU - García Martín, Elena Salobrar AU - Salazar, Juan J. AU - López-Menéndez, Celia AU - Pajuelo, Luis S. M. AU - Matamoros Felipe, José Antonio AU - Hoz Montañana, María Rosa De AU - López Cuenca, Inés AU - Elvira-Hurtado, Lorena AU - Sánchez-Puebla Fernández, Lidia AU - Sánchez-Carralero, Marina P. AU - Sanz, Marina AU - Ramírez, José M AU - Ramírez, Ana I. PY - 2025 DO - 10.1186/s12987-025-00626-z UR - https://hdl.handle.net/20.500.14352/118138 T2 - Fluids and Barriers of the CNS AB - Hydrocephalus, characterized by ventriculomegaly due to cerebrospinal fluid accumulation in the cerebral ventricles, is a co-morbidity factor in several neurodevelopmental, psychiatric and neurodegenerative diseases. Aquaporin-4 (AQP4) is crucial for... LA - eng PB - PubMed KW - AQP4 KW - Astrocyte hypertrophy KW - Hydrocephalus KW - Kidins220 KW - OCT KW - OCT angiography KW - Optic nerve KW - Phagocytic Microglia KW - Retina KW - SNX27-retromer KW - VPS35 KW - Ventriculomegaly TI - Kidins220-deficient hydrocephalus mice exhibit altered glial phenotypes and AQP4 differential regulation in the retina and optic nerve, with preserved retinal ganglion cell survival TY - journal article ER -