TY - JOUR AU - Sanz, Laura AU - Cuesta Martínez, Ángel AU - Compte, Marta AU - Álvarez Vallina, Luis PY - 2005 DO - 10.1111/j.1745-7254.2005.00135.x SN - 1671-4083 SN - 1745-7254 UR - https://hdl.handle.net/20.500.14352/114669 T2 - Acta Pharmacol Sin AB - Antibody-based therapeutics are beginning to realize the promise enclosed in their early denomination as magic bullets. Initial disappointment has turned into clinical and commercial success, and engineered antibodies currently represent over 30% of... LA - eng M2 - 641 PB - Nature KW - immunoglobulin fragments KW - monoclonal antibodies KW - antibody formation KW - gene therapy KW - recombinant proteins KW - biomedical engineering TI - Antibody engineering: facing new challenges in cancer therapy TY - journal article VL - 26 ER -