RT Journal Article
T1 Human intake assessment of triclosan associated with the daily use of polypropylene-made antimicrobial food packaging
A1 Klaiber Miguel, 
A1 Moreno Gordaliza, María Estefanía
A1 Gómez Gómez, María Milagros
A1 Marazuela Lamata, María Dolores
AB In this work, we aimed to evaluate human intake of triclosan (TCS) associated with real-life use of different brands of Microban™ microwave-safe food packaging. Calculations were based on: TCS migration data (under the worst-case foreseeable conditions), MPs abundance and TCS bioaccessibility from microplastics (MPs), leached from containers under microwave heating. Bioaccessibility studies were performed with in vitro digestionof MPs, followed by liquid-liquid extraction of TCS from digestive fluids and LC-QqQ-MS analysis yielding values of 46 ± 9%. The estimated weekly intake (EWI) of TCS ranged between 11 and 42 μg/kg body weight/week, with migration being the largest contribution (0.6–2.3 mg/week), compared to leaching of MPs (75–300 μg/week). These values represent a significant source of human exposure to TCS, emphasizing the need to harmonize the ban of TCS in food contact materials worldwide and improve compliance testing of food contact articles, particularly those marketed through online sales platforms.
PB Elsevier
YR 2024
FD 2024-04-22
LK https://hdl.handle.net/20.500.14352/104263
UL https://hdl.handle.net/20.500.14352/104263
LA eng
NO Miguel Klaiber, Estefanía Moreno-Gordaliza, M. Milagros Gómez-Gómez, M. Dolores Marazuela, Human intake assessment of triclosan associated with the daily use of polypropylene-made antimicrobial food packaging, Food Chemistry, 451, 2024, 139475,
NO Acuerdos transformativos (CRUE)
NO Ministerio de Ciencia e Innovación
DS Docta Complutense
RD 17 abr 2025