RT Journal Article
T1 Obesity can offset the cardiometabolic benefits of gestational exercise
A1 Perales, María
A1 Valenzuela, Pedro
A1 Barakat, Rubén
A1 Alejo, Lidia
A1 Cordero Rodríguez, Yaiza Adela
A1 Peláez, Mireia
A1 Lucía Mulas, Alejandro
AB Pregnancy exercise can prevent excessive gestational weight gain (EGWG), gestational diabetes mellitus (GDM) and hypertension (GH), but inter-individual variability has not been explored. We aimed to analyze the prevalence--and potential sociodemographic and medical predictors of--non-responsiveness to gestational exercise, and the association of non-responsiveness with adverse pregnancy outcomes. Among 688 women who completed a supervised light-to-moderate intensity exercise program (three ~1-h sessions/week including aerobic, resistance, and pelvic floor muscle training) until near-term, those who showed EGWG, GDM or GH were considered 'non-responders'. A low prevalence of non-responders was observed for GDM (3.6%) and GH (3.4%), but not for EGWG (24.2%). Pre-pregnancy obesity was the strongest predictor of non-responsiveness for GH (odds ratio 8.40 [95% confidence interval 3.10-22.78] and EGWG (5.37 [2.78-10.39]), whereas having a highest education level attenuated the risk of being non-responder for GDM (0.10 [0.02-0.49]). Non-responsiveness for EGWG was associated with a higher risk of prolonged labor length, instrumental/cesarean delivery, and macrosomia, and of lower Apgar scores. No association with negative delivery outcomes was found for GDM/GH. In summary, women with pre-pregnancy obesity might require from additional interventions beyond light-to-moderate intensity gestational exercise (e.g., diet and/or higher exercise loads) to ensure cardiometabolic benefits
PB Springer Nature
SN 0307-0565
YR 2020
FD 2020
LK https://hdl.handle.net/20.500.14352/99172
UL https://hdl.handle.net/20.500.14352/99172
LA eng
NO Perales, M., Valenzuela, P. L., Barakat, R., Brea Alejo, L., Cordero, Y., Peláez, M., & Lucia, A. (2021). Obesity can offset the cardiometabolic benefits of gestational exercise. International Journal of Obesity, 45(2), 342-347. https://doi.org/10.1038/S41366-020-00669-2
NO Ministerio de Economía y Competitividad (España)
NO European Commission
NO Universidad de Alcalá
DS Docta Complutense
RD 10 abr 2026