TY  - JOUR
AU  - García Linares, Sara
AU  - Huang, Pengxiang
AU  - Wierbowski, Bradley M.
AU  - Lian, Tengfei
AU  - Chan, Charlene
AU  - Jiang, Jiansen
AU  - Salic, Adrian
PY  - 2022
DO  - 10.1016/j.devcel.2022.02.008
UR  - https://hdl.handle.net/20.500.14352/130425
T2  - Developmental Cell
AB  - The dually lipidated Sonic hedgehog (SHH) morphogen signals through the tumor suppressor membrane protein Patched1 (PTCH1) to activate the Hedgehog pathway, which is fundamental in development and can-cer. SHH engagement with PTCH1 requires the GAS1...
LA  - eng
M2  - 670
PB  - Cell Press
TI  - Structural basis for catalyzed assembly of the Sonic hedgehog–Patched1 signaling complex
TY  - journal article
VL  - 57
ER  -