RT Journal Article
T1 Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic
A1 Cuñarro López, Yolanda
A1 Pintado Recarte, Pilar
A1 Hernández Martín, Concepción
A1 Payá Martínez, Pilar
A1 López Pérez, Rocío
A1 Cueto Hernández, Ignacio
A1 Ruiz Labarta, Javier
A1 Cano Valderrama, Óscar
A1 Martínez Pérez, Óscar
A1 Bravo Arribas, Coral
A1 Ortega, Miguel A.
A1 De León Luis, Juan Antonio
AB During 2020, Coronavirus Disease-19 (COVID-19) incidence fluctuated in two clear waves across the spring and autumn periods. This study was designed to compare the maternal and perinatal clinical outcomes in obstetrics patients with COVID-19 between the two waves of infection in Spain. We conducted an observational, analytical, ambispective cohort study with longitudinal follow-up of mothers with confirmed SARV-CoV-2 infection from different hospitals in our country between March–November 2020. We recruited 1295 pregnant women with SARS-CoV2 infection from 78 hospitals, 846 (65.3%) of whom were diagnosed during the first wave and 449 (34.7%) during the second wave. Our results show that patients developing COVID-19 during the first wave had more symptoms at triage, early in pregnancy with greater rates of COVID-19-related maternal morbidity; caesarean section and preterm birth in the first wave. We register two cases of maternal mortality and only during the first wave. Maternal morbidity events showed a strong link to perinatal mortality events in the first wave compared to the second wave, in which maternal morbidity was more associated with pneumonia. Likewise, maternal morbidity showed a strong correlation with perinatal morbidity events in both waves. We describe the differences between the patients’ profiles and management between the two waves and related to maternal and perinatal outcomes. Differences were also observed in the management of pregnant women with COVID-19. Thus, there were fewer caesarean sections, and maternal and perinatal morbidity events were reduced in the second wave, while the impacts of respiratory symptoms and their severity, including a greater need for maternal treatment, were greater in this last period. Identifying the impact that changes in the profile as well as in the treatment have on maternal–perinatal morbidity and mortality will help improve the well-being of our patients and their newborns.
PB MDPI
SN 2075-4426
YR 2021
FD 2021-06-25
LK https://hdl.handle.net/20.500.14352/7412
UL https://hdl.handle.net/20.500.14352/7412
LA eng
NO Cuñarro-López Y, Pintado-Recarte P, Hernández-Martín C, Paya-Martínez P, López-Pérez R, Cueto-Hernández I, et al. Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic. JPM 2021;11:599. https://doi.org/10.3390/jpm11070599.
NO This study (FIS-PI18/00912) was supported by the Instituto de Salud Carlos III (Plan Estatal de I+D+i 2013–2016) and co-financed by the European Development Regional Fund ‘‘A way to achieve Europe’’ (ERDF) and B2017/BMD-3804 MITIC-CM.
NO Unión Europea
NO Comunidad de Madrid
NO Instituto de Salud Carlos III
DS Docta Complutense
RD 30 sept 2024