RT Journal Article T1 Long COVID-19 and longer sick leave: longitudinal study of economically active patients A1 Gallo González, Virginia A1 López Padilla, Daniel Eduardo A1 Miguel Díez, Javier De A1 Suárez Escudero, Sergio A1 Ojeda Castillejo, Elena A1 Ji. Zichen, A1 Puente Maestu, Luis A1 Puente Maestu, Luis AB ntroductionSick leave was one of the numerous consequences of the COVID-19 pandemic. Given the relevance of occupational status for any individual, the aim of the study was to evaluate the impact of persistent symptoms after active infection and determine factors associated with longer sick leaves (LSLs).MethodsThis observational study focused on economically active patients attending a post-COVID outpatient clinic for persistence of symptoms or radiological alterations after active infection. The LSL temporal cut-off point was defined by the third tertile of total leave days. Median leave time was compared with the optimal sick leave time for any other viral pneumonia, estimated by the local Ministry of Employment. To determine factors associated with LSL, multivariate models were ultilised.ResultsA total of 248 patients were included. The median sick leave time for the entire population was 53 days (interquartile range (IQR) 37.0–126.5), global sum of 30 169 days; the median optimal sick leave time was 21.9 days (IQR 19.7–25.9) (p<0.05). The third tertile cut-off point for LSL was 83 days and multivariate analysis showed a significant association with dyspnoea (OR 3.26, 95% CI 1.59–6.70, p=0.0001), while physical exercise of at least 10 min·day−1 was significantly associated with shorter sick leave durations (OR 0.45, 95% CI 0.20–0.98, p=0.04).DiscussionCOVID-19 sick leave was considerably longer than that stipulated for nonsevere acute respiratory syndrome coronavirus 2 viral pneumonia. Long-COVID syndrome, especially dyspnoea, seems to be a very present factor in these patients’ inability to work. PB ERJ Journals YR 2025 FD 2025-06-02 LK https://hdl.handle.net/20.500.14352/129711 UL https://hdl.handle.net/20.500.14352/129711 LA eng NO Gallo González, V., López-Padilla, D., de Miguel Díez, J., Suárez Escudero, S., Ojeda Castillejo, E., Ji, Z., & Puente Maestu, L. (2025). Long COVID-19 and longer sick leave: longitudinal study of economically active patients. ERJ open research, 11(3), 00769-2024. https://doi.org/10.1183/23120541.00769-2024 DS Docta Complutense RD 19 abr 2026