RT Journal Article
T1 Electrospun polylactic acid-based fibers Loaded with multifunctional antibacterial biobased polymers
A1 Chiloeches, Alberto
A1 Cuervo Rodríguez, María Rocío
A1 Gil-Romero, Yolanda
A1 Fernández-García, Marta
A1 Echeverría, Coro
A1 Muñoz-Bonilla, Alexandra
AB Here, we report the development of antibacterial and compostable electrospun polylactic acid (PLA) fibers by incorporation of a multifunctional biobased polymer in the process. The multifunctional polymer was synthesized from the biosourced itaconic acid building block by radical polymerization followed by click chemistry reaction with hydantoin groups. The resulting polymer possesses triazole and hydantoin groups available for further N-alkylation and chlorination reaction, which provide antibacterial activity. This polymer was added to the electrospinning PLA solution at 10 wt %, and fiber mats were successfully prepared. The obtained fibers were surface-modified through the accessible functional groups, leading to the corresponding cationic triazolium and N-halamine groups. The fibers with both antibacterial functionalities demonstrated high antibacterial activity against Gram-positive and Gram-negative bacteria. While the fibers with cationic surface groups are only effective against Gram-positive bacteria (Staphylococcus epidermidis and Staphylococcus aureus), upon chlorination, the activity against Gram-negative Escherichia coli and Pseudomonas aeruginosa is significantly improved. In addition, the compostability of the electrospun fibers was tested under industrial composting conditions, showing that the incorporation of the antibacterial polymer does not impede the disintegrability of the material. Overall, this study demonstrates the feasibility of this biobased multifunctional polymer as an antibacterial agent for biodegradable polymeric materials with potential application in medical uses.
PB American Chemical Society
SN 2637-6105
YR 2022
FD 2022
LK https://hdl.handle.net/20.500.14352/101832
UL https://hdl.handle.net/20.500.14352/101832
LA eng
NO A. Chiloeches, R. Cuervo-Rodríguez, Y. Gil-Romero, F. López-Fabal, M. Fernández-García, C. Echeverría, A. Muñoz-Bonilla. Electrospun polylactic acid-based fibers loaded with multifunctional antibacterial biobased polymers. ACS Appl. Polym. Mater. 2022 Aug 26; 4 (9): 6543-52
NO Ministerio de Ciencia, Innovación y Universidades (España)
NO European Commission
NO Consejo Superior de Investigaciones Científicas
DS Docta Complutense
RD 26 ene 2026