RT Journal Article T1 Diagnostic performance of cone-beam computed tomography to diagnose in vivo/in vitro root resorption: a systematic review and meta-analysis A1 Baena de la Iglesia, Teresa A1 Yáñez Vico, Rosa María A1 Iglesias Linares, Alejandro AB BackgroundThis review analyses the diagnostic performance of cone-beam computed tomography (CBCT) for the in vivo/in vitro detection of external root resorption (ERR) and critically analyses current and past methods of measuring or classifying ERR in vivo/in vitro in terms of radiation doses and cumulative radiation risks.MethodsA diagnostic test accuracy (DTA) protocol was used for a systematic review of diagnostic methods following PRISMA guidelines. The protocol was registered with PROSPERO (ID: CRD42019120513). A thorough and exhaustive electronic search of 6 core electronic databases was performed, applying the ISSG Search Filter Resource. The eligibility criteria were designed [problem-intervention-comparison-outcomes (PICO) statement: Population, Index test, Comparator, Outcome] and methodological quality was assessed by QUADAS-2.ResultsSeventeen papers were selected from a total of 7841 articles. Six in vivo studies were assessed as having a low risk of bias. The overall sensitivity and specificity of CBCT for diagnosis of ERR was 78.12% and 79.25%, respectively. The highest and lowest sensitivity and specificity of CBCT for diagnosis of external root resorption are 42%-98% and 49.3%-96.3%.DiscussionMost of the selected studies reported quantitative diagnoses with single linear measurements of ERR even though multislice radiographs were available. The cumulative radiation dose (μS) to radiation-sensitive structures, such as the bone marrow, brain and thyroid, was observed to increase using the 3-dimensional (3D) radiography methods reported.ConclusionsThe highest and lowest sensitivity and specificity of CBCT for diagnosis of external root resorption are 42%-98% and 49.3%-96.3%. The minimum and maximum effective doses of dental CBCT for external root resorption diagnosis are 34 μSv and 1073 μSv. PB Elsevier SN 15323382 YR 2022 FD 2022-11-08 LK https://hdl.handle.net/20.500.14352/72920 UL https://hdl.handle.net/20.500.14352/72920 LA eng NO CRUE-CSIC (Acuerdos Transformativos 2022) DS Docta Complutense RD 28 sept 2024