RT Journal Article T1 Supra and subgingival application of antiseptics or antibiotics during periodontal therapy A1 Figuero Ruiz, Elena A1 Serrano, Jorge A1 Arweiler, Nicole Birgit A1 Auschill, Thorsten Mathias A1 Gürkan, Ali A1 Emingil, Gülnur AB Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient's risk factors and the debridement of supra and subgingival biofilm. This debridement can be performed with or without the use of some adjuvant therapies, including physical or chemical agents, host modulating agents, subgingivally locally delivered antimicrobials, or systemic antimicrobials. Therefore, the main aim of this article is to review in a narrative manner the existing literature regarding the adjuvant application of local agents, either subgingivally delivered antibiotics and antiseptics or supragingivally applied rinses and dentifrices, during the different steps in periodontal therapy performed in Europe. PB Wiley SN 0906-6713 YR 2023 FD 2023-09-28 LK https://hdl.handle.net/20.500.14352/117829 UL https://hdl.handle.net/20.500.14352/117829 LA eng NO Figuero E, Serrano J, Arweiler NB, Auschill TM, Gürkan A, Emingil G. Supra and subgingival application of antiseptics or antibiotics during periodontal therapy. Periodontol 2000. 2023 Sep 28. doi: 10.1111/prd.12511 DS Docta Complutense RD 8 abr 2025