RT Journal Article T1 Updating gender differences in the control of homeostatic and hedonic food intake: Implications for binge eating disorder A1 Garrido Novelle, Marta A1 Diéguez, Carlos AB In an obesity pandemic context, eating disorders (ED) have arisen as serious illnesses associated with severe disturbances and has a clear gender dependent bias. In this manuscript, we provide an overview of the oestrogen role in the homeostatic and hedonic control of food intake. We draw attention to the role of oestrogens in the various reward processes and their possible implication in the development of ED, a condition much more common in women. In here, we have summarized the most relevant studies conducted in animal models over the last few years. In particular, we want to emphasize on the importance of continuing thorough investigations in female animal models. We believe that understanding the molecular mechanisms that regulate gender differences in food intake may provide new potential targets for ED treatment. PB Elsevier SN 0303-7207 YR 2019 FD 2019 LK https://hdl.handle.net/20.500.14352/94772 UL https://hdl.handle.net/20.500.14352/94772 LA eng NO Novelle, Marta G., y Carlos Diéguez. «Updating Gender Differences in the Control of Homeostatic and Hedonic Food Intake: Implications for Binge Eating Disorder». Molecular and Cellular Endocrinology, vol. 497, noviembre de 2019, p. 110508. https://doi.org/10.1016/j.mce.2019.110508. NO This work has been supported by grants from Ministerio de Economía y Competitividad (CD BFU 2017-87721), Xunta de Galicia (ED431, 2017/030). Centro de Investigación Biomédica en Red (CIBER) de Fisiopatología de la Obesidad y Nutrición (CIBERobn). CIBERobn is an initiative of the Instituto de Salud Carlos III (ISCIII) of Spain, which is supported by FEDER funds. NO Instituto de Salud Carlos III NO Xunta de Galicia NO Ministerio de Economía y Competitividad (España) NO European Commission DS Docta Complutense RD 8 abr 2025