RT Journal Article T1 Optical and aberrometric evaluation of a new enhanced monofocal intraocular lens with isofocal optic design A1 Pérez Sanz, Lidia A1 Charbel Yaghi, Carla A1 Poyales, Francisco A1 Garzón Jiménez, Nuria AB Purpose: To evaluate the optical and aberrometric outcomes of an enhanced monofocal intraocular lens (ISOPure) compared with those of a standard monofocal lens (MicroPure) having the same platform and material.Methods: A prospective, comparative and randomised clinical study. A total of 28 eyes of 28 patients were randomly assigned to either group. Monocular visual acuity (VA) was measured at distance and intermediate under photopic and mesopic conditions. Aberrometry was analysed for 3.0-, 4.0-, 4.5- and 5.0 mm pupils. The contrast sensitivity defocus curve was measured for 3.0- and 4.5-mm pupils, while the modulation transfer function (MTF) and Strehl ratio (SR) were assessed with a double-pass system. All measurements were performed monocularly 3 months after surgery.Results: No significant differences were found for distance VA. Under photopic conditions, intermediate VA was better with the ISOPure lens, while no significant differences were found between the lenses under mesopic conditions. Internal and total aberrations were higher for the ISOPure lens. No significant differences were found for corneal aberrations. Additionally, both the contrast sensitivity defocus curve and optical quality showed similar behaviour for each lens, with the MTF cut-off frequency exceeding 30 c/deg in both cases.Conclusion: The isofocal ISOPure lens enhanced intermediate VA without affecting distance VA under photopic conditions. Moreover, there were no significant differences in visual quality between the ISOPure and MicroPure lenses, despite the former exhibiting higher internal and total aberrations than the monofocal model. PB Wiley SN 0275-5408 SN 1475-1313 YR 2024 FD 2024-02-13 LK https://hdl.handle.net/20.500.14352/101737 UL https://hdl.handle.net/20.500.14352/101737 LA eng NO Pérez-Sanz L, Charbel C, Poyales F, Garzón N. Optical and aberrometric evaluation of a new enhanced monofocal intraocular lens with isofocal optic design. Ophthalmic Physiol Opt. Published online February 13, 2024. doi:10.1111/opo.13287 NO Version of Record online: 13 February 2024; Manuscript accepted: 30 January 2024; Manuscript revised: 29 January 2024; Manuscript received: 05 September 2023. DS Docta Complutense RD 1 ago 2024