TY - JOUR AU - Quijada Álamo, Miguel AU - Hernández Sánchez, María AU - Alonso Pérez, Verónica AU - Rodríguez Vicente, Ana E. AU - García Tuñón, Ignacio AU - Martín Izquierdo, Marta AU - Hernández Sánchez, Jesús María AU - Herrero, Ana B. AU - Bastida, José María AU - San Segundo, Laura AU - Gruber, Michaela AU - García, Juan Luis AU - Yin, Shanye AU - Hacken, Elisa ten AU - Benito, Rocío AU - Ordóñez, José Luis AU - Wu, Catherine J. AU - Hernández-Rivas, Jesús María PY - 2020 DO - 10.1038/s41375-020-0714-3 SN - 0887-6924 SN - 1476-5551 UR - https://hdl.handle.net/20.500.14352/110927 T2 - Leukemia AB - The deletion of 11q (del(11q)) invariably comprises ATM gene in chronic lymphocytic leukemia (CLL). Concomitant mutations in this gene in the remaining allele have been identified in 1/3 of CLL cases harboring del(11q), being the biallelic loss of ATM... LA - eng M2 - 1599 PB - Nature Publishing Group TI - CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition TY - journal article VL - 34 ER -