RT Journal Article
T1 Interaction between acetylsalicylic acid and a cationic amphiphile model: an experimental approach using surface techniques
A1 Flores-Sánchez, R.
A1 Bigorra-Mir, M.
A1 Gámez, F.
A1 Lopes-Costa, T.
A1 Argudo, P. G.
A1 Martín-Romero, M. T.
A1 Camacho, L.
A1 Pedrosa, J. M.
AB Mechanical and morphological effects of monolayers of octadecylamine upon aspirin adsorption are monitored by Langmuir isotherms measurements and Brewster angle microscopy. Aspirin induced a notable expansion of the corresponding isotherms and a concentration-dependence of the mechanical stability of the films as a consequence of the subtle balance between the solubility of the amine and the monolayer stabilization induced by the ion-pairs, as corroborated by Brewster Angle Microscopy images. The incorporation of the aspirin into the interface was confirmed by UV–vis reflection spectroscopy. Some comments on the feasibility of using aliphatic amines for drug delivery of anionic species are presented.
PB Elsevier
SN 0009-2614
YR 2023
FD 2023
LK https://hdl.handle.net/20.500.14352/108013
UL https://hdl.handle.net/20.500.14352/108013
LA eng
NO R. Flores-Sánchez, M. Bigorra-Mir, F. Gámez, T. Lopes-Costa, P.G. Argudo, M.T. Martín-Romero, L. Camacho, J.M. Pedrosa, Interaction between acetylsalicylic acid and a cationic amphiphile model: An experimental approach using surface techniques, Chemical Physics Letters, Volume 819, 2023, 140450, ISSN 0009-2614, https://doi.org/10.1016/j.cplett.2023.140450.
DS Docta Complutense
RD 6 abr 2025