TY - JOUR AU - Estañ, María Cristina AU - Calviño, Eva AU - Blas, Elena de AU - Boyano Adánez, María del Carmen AU - Mena Fernández, María Luz AU - Gómez Gómez, María Milagros AU - Rial, Eduardo AU - Aller, Patricio PY - 2012 DO - doi.org/10.1016/j.bcp.2012.09.022 SN - 0006-2952(Print) 1873-2968 (Online) UR - https://hdl.handle.net/20.500.14352/42639 T2 - Biochemical pharmacology AB - While the anti-tumor efficacy of 2-deoxy-D-glucose (2-DG) is normally low in monotherapy, it may represent a valuable radio- and chemo-sensitizing agent. We here demonstrate that 2–10 mM 2-DG cooperates with arsenic trioxide (ATO) and other antitumor... LA - eng M2 - 1604 PB - Elsevier KW - 2-Deoxy-D-glucose KW - Arsenic trioxide KW - Apoptosis KW - Protein kinases KW - Leukemia cells TI - 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: Involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/ AMPK signaling pathways TY - journal article VL - 84 ER -