RT Journal Article T1 Mild and High-Yielding Synthesis of β-Keto Esters and β-Ketoamides A1 Sridharan, Vellaisamy A1 Menéndez Ramos, José Carlos A1 Ruiz Serrano, Miriam AB In the presence of sodium acetate, the reaction between 2,2,6-trimethyl-4H-1,3-dioxin-4-one and secondary or tertiary alcohols (including chiral ones) or primary or secondary amines could be carried out in refluxing tetrahydrofuran, under much milder conditions than those described in the literature. In these new conditions, side products normally observed using the traditional protocol were avoided, and b-keto esters and b-ketoamides were normally obtained in quantitative yields PB Thieme Gruppe SN 0039-7881 YR 2009 FD 2009 LK https://hdl.handle.net/20.500.14352/129002 UL https://hdl.handle.net/20.500.14352/129002 LA eng NO Sridharan V, Ruiz M, Menéndez J. Mild and High-Yielding Synthesis of β-Keto Esters and β-Ketoamides. Synthesis 2010;2010:1053–7. https://doi.org/10.1055/s-0029-1217135. NO Ministerio de Ciencia, Innovación y Universidades (España) NO Universidad Complutense de Madrid NO Comunidad de Madrid DS Docta Complutense RD 31 dic 2025