RT Journal Article
T1 Exploring the synergy of ionic liquids and lipase in sustainable enzymatic engineering
A1 Castro Vicerra, Viviane de
A1 Leandro Fernandes Melo, Rafael
A1 Simão Neto, Francisco
A1 Carlos de Castro, Erico
A1 Bessa Sales, Misael
A1 Gonçalves de Sousa Junior, Paulo
A1 Nascimento Dari, Dayana
A1 Izaias da Silva Aires, Francisco
A1 Moreira dos Santos, Kaiany
A1 de França Serpa, Juliana
A1 Kim, Tak H.
A1 Fernández Lucas, Jesús
A1 Cristiane Martins de Souza, Maria
A1 dos Santos, Jose C.S.
AB Ionic liquids (ILs) are widely used in many applications. Still, their use in enzyme engineering is particularly notable due to their environmentally friendly nature and efficient replacement of conventional organic solvents. Recently, lipase has emerged as an environmentally friendly catalyst. Nevertheless, using Lipases in the presence of ILs has led to a remarkable activity enhancement, making it a sustainable and non-harmful approach. This study conducted a bibliometric review of research articles published between 2010 and 2022 concerning the use of ILs in lipase-catalyzed reactions. The analysis was based on 206 publications retrieved from the Web of Science Core Collection (WoS) database., which were analyzed using different software tools, such as VOSviewer, CiteSpace, and ArcGIS. Key findings included that over half of the publications originated from other countries, notably China (around 36.4%), the United States, Spain, and France. As a result of this bibliometric analysis, four emerging trends were identified: namely: i) lipase-catalyzed synthesis, ii) the use of deep eutectic solvent, iii) the application of ILs in secondary alcohol reactions, iv) the use of ILs as green solvents, and iv) the enzymatic ring-opening polymerization. The study also evaluated the most prominent authors, articles, and institutions that provide comprehensive data on up-to-date research on ILs and lipases. It is noted that the studies identify significant advantages in this field, showing a positive trend of promising results, especially with the development of improved and environmentally friendly processes.
PB Elsevier
SN 0167-7322
YR 2024
FD 2024
LK https://hdl.handle.net/20.500.14352/108616
UL https://hdl.handle.net/20.500.14352/108616
LA eng
NO De Castro Bizerra, Viviane, et al. «Exploring the Synergy of Ionic Liquids and Lipase in Sustainable Enzymatic Engineering». Journal of Molecular Liquids, vol. 399, abril de 2024, p. 124373. DOI.org (Crossref), https://doi.org/10.1016/j.molliq.2024.124373.
NO Fundação Cearense de Apoio ao Desenvolvimento Cientif́ico e Tecnológico
NO Conselho Nacional de Desenvolvimento Científico e Tecnológico
NO Coordenação de Aperfeiçoamento de Ensino Superior
DS Docta Complutense
RD 6 abr 2025