RT Journal Article
T1 Strengthening the relationship between intractable plantar keratosis and human papillomavirus
A1 Alou Cervera, Luis
A1 Becerro De Bengoa Vallejo, Ricardo
A1 Losa Iglesias, Marta Elena
A1 Moreno, Juan
A1 Sánchez Gómez, Rubén
A1 González Hidalgo, Natalia
A1 Sevillano Fernández, David
AB The aim of the study was to determine the presence of human papillomavirus (HPV) in patients with intractable plantar keratosis (IPK) by comparing the histopathological findings of biopsies. A prospective, observational, and concordance study was carried out. Three different specimens were taken from each IPK. A first punch was sent for histopathological examination, and a second punch and a superficial skin scraping were both sent for HPV  polymerase chain reaction (PCR) and type determination. A total of 51 patients were included. From the histopathological examination, it was determined that 35 (68.6%) samples were diagnosed as warts and 16 (31.3%) as keratosis. However, the presence of HPV was confirmed by PCR in 49 (96.1%) and in 42 (82.4%) samples obtained by punch and superficial scraping, respectively. In the 49 PCR‐positive samples, the most common HPV types were HPV1, HPV2, HPV27, HPV57, and HPV65, accounting for 81.6% of the samples. In conclusion, this study demonstrates that HPV infection and IPK lesions are very closely related. Although we cannot confirm that HPV is the cause of the development of IPK, the high prevalence of HPV observed in these lesions calls for a change to the procedures for managing IPK.
PB Wiley
SN 0146-6615
SN 1096-9071
YR 2024
FD 2024-01-31
LK https://hdl.handle.net/20.500.14352/98030
UL https://hdl.handle.net/20.500.14352/98030
LA eng
NO Alou L, Becerro-de-Bengoa-Vallejo R, Losa-Iglesias ME, Moreno J, Sánchez-Gómez R, González N, Sevillano D. Strengthening the relationship between intractable plantar keratosis and human papillomavirus. J Med Virol. 2024 Feb;96(2):e29431.
DS Docta Complutense
RD 19 jul 2024