RT Journal Article
T1 Utility of Blood Parameters to Detect Complications during Long-Term Follow-Up in Patients with Diabetic Foot Osteomyelitis
A1 Tardaguila García, Aroa
A1 García Álvarez, Yolanda
A1 García Morales, Esther Alicia
A1 Álvaro Afonso, Francisco Javier
A1 Sanz Corbalán, Irene
A1 Lázaro Martínez, José Luis
AB The evidence is still unclear regarding the role of blood parameters in detecting complications in patients who suffer from diabetic foot osteomyelitis (DFO). In this study, the aim was to identify the capacity of different blood parameters in the diagnosis and prediction of the onset of complications. A cross-sectional prospective study was carried out with 116 DFO patients. The following blood parameters were evaluated during 1 year of follow-up: leukocytes, neutrophils, lymphocytes, monocytes, eosinophils, basophils, erythrocyte sedimentation rate (ESR), glycemia, glycosylated hemoglobin, C-reactive protein (CRP), alkaline phosphatase, albumin, and creatinine. Complication events were assessed for each participant during the study period. We investigated the association between blood parameter values and the onset of complication events by conducting a receiver operating characteristic curve analysis. Eighty-five (73.3%) patients developed complications. Regarding blood parameters, higher values of lymphocytes and albumin were predictive factors at the 12-month follow-up once the ulcer had healed. Higher values of ESR had predictive and diagnostic value for the onset of complication events, and higher values of CRP and hyperglycemia were diagnostic factors since they were elevated during the occurrence of an event. In conclusion, after suffering from DFO, the elevation of lymphocytes, ESR, CRP, albumin, and glycemia could be useful in detecting and diagnosing patients who are likely to develop a complication. Serial blood tests are a useful tool for early detection by healthcare professionals to prevent complications.
PB MDPI
YR 2020
FD 2020-11-22
LK https://hdl.handle.net/20.500.14352/119447
UL https://hdl.handle.net/20.500.14352/119447
LA eng
NO Tardáguila-García A, García Álvarez Y, García-Morales E, Álvaro-Afonso FJ, Sanz-Corbalán I, Lázaro-Martínez JL. Utility of Blood Parameters to Detect Complications during Long-Term Follow-Up in Patients with Diabetic Foot Osteomyelitis. J Clin Med. 2020 Nov 22;9(11):3768. doi: 10.3390/jcm9113768. PMID: 33266483; PMCID: PMC7700132.
NO Special Issue Diabetic Foot Complications: Current Challenges and Future Prospects-Part I
DS Docta Complutense
RD 21 dic 2025