RT Journal Article
T1 Efficacy of Povidone Iodine Against Microbial Biofilms in Breast Implants With Different Textures: Results From an in vitro Study
A1 Fernández Ibarburu, Borja
A1 Díaz Navarro, Marta
A1 Ibarra, Gorka
A1 Rivera, Andrés
A1 Hafian Al-Homsi, Rama
A1 Irigoyen, Álvaro
A1 Carrillo, Raquel
A1 Pérez Cano, Rosa
A1 Muñoz García, Patricia Carmen
A1 García Ruano, Ángela
A1 Lasso Vázquez, José María
A1 Guembe, María
AB Background:In the practice of breast augmentation and reconstruction, implant irrigation with various solutions has been widely used to prevent infection and capsular contracture, but to date, there is no consensus on the optimal protocol to use. Recently, application of povidone iodine (PI) for 30 min has shown in vitro to be the most effective irrigating formula in reducing contamination in smooth breast implants. However, as 30 min is not feasible intraoperatively, it is necessary to determine whether shorter times could be equally effective as well as to test it in both smooth and textured implants.Methods:We tested the efficacy of 10% PI at 1', 3', and 5' against biofilms of 8 strains (2 ATCC and 6 clinical) of Staphylococcus spp. on silicone disks obtained from Mentor®and Polytech®implants of different textures. We analyzed the percentage reduction of cfu counts, cell viability and bacterial density between treatment (PI) and control (sterile saline, SS) groups for each time of application. We consider clinical significance when > 25% reduction was observed in cell viability or bacterial density.Results:All textured implants treated with PI at any of the 3 exposure times reduced 100% bacterial load by culture. However, none of the implants reached enough clinical significance in percentage reduction of living cells. Regarding bacterial density, only 25-50 μm Polytxt®Polytech®implants showed significant reduction at the three PI exposure times.Conclusion:PI is able to inhibit bacterial growth applied on the surface of breast implants regardless of the exposure time. However, no significant reduction on living cells or bacterial density was observed. This lack of correlation may be caused by differences in texture that directly affect PI absorption.
PB PCM
SN 1664-302X
YR 2022
FD 2022
LK https://hdl.handle.net/20.500.14352/131813
UL https://hdl.handle.net/20.500.14352/131813
LA eng
NO Fernández-Ibarburu, B., Díaz-Navarro, M., Ibarra, G., Rivera, A., Hafian, R., Irigoyen, Ã., Carrillo, R., Pérez-Cano, R., Muñoz, P., García-Ruano, Á., Lasso, J. M., & Guembe, M. (2022). Efficacy of Povidone Iodine Against Microbial Biofilms in Breast Implants With Different Textures: Results From an in vitro Study. Frontiers in microbiology, 13, 868347. https://doi.org/10.3389/fmicb.2022.868347
NO MG was supported by the Miguel Servet Program (ISCIIIMICINN, MSII18/00008) from the Health Research Fund (FIS) of the Carlos III Health Institute (ISCIII), Madrid, Spain
NO MD-N was supported by the Consejería de Educación, Juventud y Deporte de la Comunidad de Madrid and Fondo Social Europeo (PEJD-2020-AI_BMD-17971).
NO The study was partially financed by grants from the Fundación Mutua Madrileña (FMM21/01).
DS Docta Complutense
RD 20 mar 2026