RT Journal Article
T1 Fatal toxoplasmosis in a captive squirrel monkey (Saimiri boliviensis) in  Portugal
A1 Salas-Fajardo, Martha Ynés
A1 Benavides, Julio
A1 Azevedo, Alexandre
A1 Figueiras, Paulo
A1 Monteiro, Madalena
A1 Orge, Leonor
A1 Mendoça, Paula
A1 Carvalho, Paulo
A1 Waap, Helga
A1 Ortega Mora, Luis Miguel
A1 Calero Bernal, Rafael
AB New World monkeys are especially vulnerable to develop severe clinical manifestations and succumb to acute toxoplasmosis. This study aimed to describe the histopathological findings and genotypic characterization of the Toxoplasma gondii strain involved in a lethal case occurring in a zoo-housed black-capped squirrel monkey (Saimiri boliviensis) in Portugal. Cyst-like structures suggestive of Sarcocystidae parasites and acute injuries in liver and brain were observed by light microscopy examination. By immunohistochemistry, calprotectin, T. gondii antigen and Iba1 antigen had a positive signaling in lung, liver and brain tissues. Toxoplasma gondii B1, ITS1 and 529 repetitive element fragments amplifications together with the genotyping of 13 microsatellite markers confirmed a systemic T. gondii infection linked to a non-clonal type II strain. This description is consistent to the majority T. gondii strains circulating in Europe.
PB Springer Nature
SN 0165-7380
YR 2023
FD 2023-07-21
LK https://hdl.handle.net/20.500.14352/87407
UL https://hdl.handle.net/20.500.14352/87407
LA eng
NO Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. LMO-M, and RC-B are part of the TOXOSOURCES consortium supported by the funding from the European Union's Horizon 2020 Research and Innovation Programme under the Grant Agreement No 773830: One Health European Joint Programme.
DS Docta Complutense
RD 15 may 2025