TY - JOUR AU - González Hidalgo, Natalia AU - Sevillano Fernández, David AU - Alou Cervera, Luis AU - Cafini, Fabio AU - Gimenez, María José AU - Gómez-Lus Centelles, María Luisa AU - Prieto Prieto, José AU - Aguilar, Lorenzo PY - 2013 DO - 10.1093/jac/dkt185 SN - 0305-7453 UR - https://hdl.handle.net/20.500.14352/106757 T2 - Journal of Antimicrobial Chemotherapy AB - Objectives: To explore serum and tissue pharmacodynamics of linezolid versus vancomycin against methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates with different MBC/MIC ratios.Methods: Five strains (vancomycin MIC/MBCs, mg/L) were... LA - eng M2 - 2291 PB - Oxford University Press KW - MRSA KW - Diabetic foot infections KW - Pharmacodynamic simulations KW - Tolerance TI - Influence of the MBC/MIC ratio on the antibacterial activity of vancomycin versus linezolid against methicillin-resistant Staphylococcus aureus isolates in a pharmacodynamic model simulating serum and soft tissue interstitial fluid concentrations reported in diabetic patients TY - journal article VL - 68 ER -