RT Journal Article
T1 Geometrical limits for UV-C inactivation of pathogens
A1 Quintana Benito, Jaime
A1 Álvarez Fernández-Balbuena, Antonio
A1 Martínez Antón, Juan Carlos
A1 Vázquez Moliní, Daniel
A1 Prada, Luis
A1 Estrada, Luis
A1 Alda Serrano, Javier
AB The inactivation of pathogens through the irradiation of ultraviolet light depends on how light propagates within the medium where the microorganism is immersed. A simple geometrical optics analysis, and a fluence evaluation reveal some reservoirs where the pathogen may hide and be weakly exposed to the incoming radiation. This geometrical hide-outs also generate a tail in the plot of the total inactivation plot vs. the incoming fluence. We have analyzed these facts using geometrical optics principles and illumination engineering computational packages. The results obtained from previous biomedical measurements involving SARS-CoV-2 have been used to evaluate the inactivation degree for an spherical geometry applicable to airborne pathogens, and for an spherical cap geometry similar to that used in biomedical experiments. The case presented here can be seen as the worst-case scenario applicable under collimated illumination.
PB Elsevier
SN 0030-4026
YR 2022
FD 2022-10-30
LK https://hdl.handle.net/20.500.14352/71304
UL https://hdl.handle.net/20.500.14352/71304
LA eng
NO CRUE-CSIC (Acuerdos Transformativos 2021)
NO Comunidad de Madrid
DS Docta Complutense
RD 12 may 2025